publications  journal articles Boon Group publications 5. Muralidharan, S.; Boon, E.M.* (2012) Heme flattening is sufficient for signal transduction in the H-NOX family. Journal of the American Chemical Society, DOI:10.1021/ja211576b. 4. Dai, Z.; Boon, E.M.* (2011) Probing the local electronic and geometric properties of the heme iron center in an O2-binding H-NOX domain. Journal of Inorganic Biochemistry, DOI: 10.1016/j.jinorgbio.2011.03.002. 3. Dai, Z.; Boon, E.M.* (2010) Sensitive and selective detection of cyanide using an H-NOX domain. Journal of the American Chemical Society, DOI: 10.1021/ja101674z. 2. Liu, N.; Pak, T.; Boon, E.M.* (2010) Characterization of a diguanylate cyclase from Shewanella woodyi with cyclase and phosphodiesterase activities. Molecular BioSystems, DOI: 10.1039/c002246b. 1. Boon, E.M.* (2009) Review of Biochemistry of Signal Transduction and Regulation, Fourth Enlarged and Improved Edition, by Gerhard Krauss for The Quarterly Review of Biology, 84 (2), 200. Postdoctoral publications 9. Tran, R.; Weinert, E.E.; Boon, E.M.; Mathies, R.A.; Marletta, M.A. (2011) Determinants of the heme-CO vibrational modes in the H-NOX family. Biochemistry, 50, 6519-6530. 8. Tran, R.; Boon, E.M.; Marletta, M.A.; Mathies, R.A. (2009) Resonance Raman spectra of an O2-binding H-NOX domain reveals heme relaxation upon mutation. Biochemistry, 48, 8568-8577. 7. Olea, C.; Boon, E.M.; Pellicena, P.; Kuriyan, J.; Marletta, M.A. (2008) Probing the function of heme distortion in the H-NOX family. American Chemical Society Chemical Biology, 3, 703-710. 6. Boon, E.M.; Marletta, M.A. (2006) Sensitive and selective detection of nitric oxide using an H-NOX domain. Journal of the American Chemical Society, 128, 10022-10023. 5. Boon, E.M.; Davis, J.H.; Karow, D.S.; Huang, S.H.; Tran, R.; Miazgowicz, M.M.; Mathies, R.; Marletta, M.A. (2006) Characterization of NO binding to prokaryotic homologs of the sGC 1 H-NOX domain. Journal of Biological Chemistry, 281, 21892-21902. 4. Boon, E.M.; Marletta, M.A. (2005) Ligand discrimination in soluble guanylate cyclase and the H-NOX family of heme sensor proteins. Current Opinion in Chemical Biology, 9, 441-446. 3. Boon, E.M.; Huang, S.H.; Marletta, M.A. (2005) A molecular basis for NO selectivity in soluble guanylate cyclase. Nature Chemical Biology, 1, 53-59. 2. Boon, E.M.; Marletta, M.A. (2005) Ligand specificity of H-NOX domains: From sGC to bacterial NO sensors. Journal of Inorganic Biochemistry, 99, 892-902. 1. Pellicena, P.; Karow, D.S.; Boon, E.M.; Marletta, M.A.; Kuriyan, J. (2004) Crystal structure of an oxygen-binding heme domain related to soluble guanylate cyclases. Proceedings of the National Academy of Science USA, 101, 12854-12859. Graduate publications 13. Yavin, Eylon; Boal, Amie K.; Stemp, E.D.A.; Boon, E.M.; O’Shea, V.L.; David, S.S.; Barton, J.K. (2005) Protein-DNA charge transport: Redox activation of a DNA repair protein by guanine radical. Proceedings of the National Academy of Science USA, 102, 3546-3551. 12. Boon, E.M.; Barton, J.K. (2003) DNA electrochemistry as a probe of base pair stacking in A-, B-, and Z-form DNA. Bioconjugate Chemistry, 14, 1140-1147. 11. Boon, E.M.; Barton, J.K.; Bhaghat, V.; Nersissian, M.; Wang, W.; Hill, M.G. (2003) Reduction of ferricyanide by methylene blue at a DNA-modified rotating-disk electrode. Langmuir, 19, 9255-9259. 10. Boon, E.M.; Livingston, A.L.; Chmiel, N.H.; David, S.S.; Barton, J.K. (2003) DNA-mediated charge transport for DNA repair. Proceedings of the National Academy of Science USA, 100, 12543-12547. 9. Boon, E.M.; Jackson, N.M.; Wightman, M.D.; Kelley, S.O.; Hill, M.G.; Barton, J.K. (2003) Intercalative stacking: A critical feature of DNA charge transport electrochemistry. Journal of Physical Chemistry B, 107, 11805-11812. 8. Boon, E.M.; Kisko, J.L.; Barton, J.K. (2002) Detection of base mismatches using intercalators. Methods in Enzymology, 353, 506-522. 7. Boon, E.M.; Barton, J.K. (2002) Charge transport in DNA. Current Opinion in Structural Biology, 12, 320-329. 6. Boon, E.M.; Barton, J.K.; Pradeepkumar, P.I.; Isaksson, J.; Petit, C.; Chattopadhyaya, J. (2002) An electrochemical probe of DNA stacking in an antisense oligonucleotide containing a C3’-endo locked sugar. Angewandte Chemie International Edition, 114, 3552-3555. 5. Boon, E.M.; Pope, M.A.; Williams, S.D.; David, S.S.; Barton, J.K. (2002) DNA-mediated charge transport as a probe of MutY/DNA interaction. Biochemistry, 41, 8464-8470. 4. Boon, E.M.; Salas, J.E.; Barton, J.K. (2002) An electrical probe of DNA-protein interactions on DNA-modified surfaces. Nature Biotechnology, 20, 282-286. 3. Sam, M.†; Boon, E.M.†; Barton, J.K.; Hill M.G.; Spain, M.S. (2001) Morphology of 15-mer duplexes tethered to Au(111) through 3' and 5' linkages via scanning probe microscopy. Langmuir, 17, 5727-5730. †equal authorship 2. Boon, E.M.; Ceres, D.M.; Drummond, T.G.; Hill, M.G.; Barton, J.K. (2000) Mutation detection by electrocatalysis at DNA-modified electrodes. Nature Biotechnology, 18, 1096-1100. 1. Kelley, S.O.; Boon, E.M.; Barton, J.K.; Jackson, N.M.; Hill, M.G. (1999) Single base mismatch detection based on charge transduction through DNA. Nucleic Acids Research, 27, 4830-4837.  patents 4. Cary, S.P.L.; Boon, E.M.; Winger, J.; Marletta, M.A. (2007) Compositions and methods for the delivery of oxygen. Application number/Patent number 07795174.7 – 2107 PCT/US2007012184. 3. Cary, S.P.L.; Boon, E.M.; Winger, J.; Marletta, M.A. (2007) Compositions and methods for the delivery of nitric oxide. Application number/Patent number 07795153.1 – 2107 PCT/US2007012133. 2. Boon, E.M.; Marletta, M.A. (2005) Sensitive and selective detection of NO using an H-NOX domain. Patent disclosure submitted, UC case number B06-064. 1. Barton, J.K.; Boon, E.M.; Kelley, S.O.; Hill, M.G. (2001) Electrochemical sensor using intercalative, redox-active moieties. U.S. Patent application number 091753,362.  theses 5. Dai, Z., Ph.D. 2011, Stony Brook University. The Molecular Basis of Diatomic Molecule Binding by H-NOX Domains. 4. Gorgani, F., M.S. 2010, Stony Brook University. Determining ligand-binding induced conformational changes in H-NOX domains. 3. Georgiou, S., M.Phil. 2009, Stony Brook University. 2. Christiansen, M., M.S. 2008, Stony Brook University. Towards understanding the biological role of the conserved H-NOX domain in bacteria. 1. Boon, E.M., Ph.D. 2003, California Institute of Technology. Electrochemical sensors based on DNA-mediated charge transport chemistry.